G-Protein Signaling Triggered by R5 Human Immunodeficiency Virus Type 1 Increases Virus Replication Efficiency in Primary T Lymphocytes

The binding of R5 envelope to CCR5 during human immunodeficiency virus type 1 (HIV-1) entry provokes cell activation, which has so far been considered to have no effect on virus replication, since signaling-defective CCR5 molecules have been shown to function normally as HIV-1 coreceptors on transfo...

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Detalhes bibliográficos
Main Authors: Lin, Yea-Lih, Mettling, Clément, Portalès, Pierre, Réant, Brigitte, Clot, Jacques, Corbeau, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1143625/
https://ncbi.nlm.nih.gov/pubmed/15919952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.12.7938-7941.2005
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