Small-Molecule Inhibition of HIV pre-mRNA Splicing as a Novel Antiretroviral Therapy to Overcome Drug Resistance

The development of multidrug-resistant viruses compromises antiretroviral therapy efficacy and limits therapeutic options. Therefore, it is an ongoing task to identify new targets for antiretroviral therapy and to develop new drugs. Here, we show that an indole derivative (IDC16) that interferes wit...

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Bibliografiske detaljer
Main Authors: Bakkour, Nadia, Lin, Yea-Lih, Maire, Sophie, Ayadi, Lilia, Mahuteau-Betzer, Florence, Nguyen, Chi Hung, Mettling, Clément, Portales, Pierre, Grierson, David, Chabot, Benoit, Jeanteur, Philippe, Branlant, Christiane, Corbeau, Pierre, Tazi, Jamal
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2007
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042022/
https://ncbi.nlm.nih.gov/pubmed/17967062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.0030159
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