Interactive effects of age and estrogen on cognition and pyramidal neurons in monkey prefrontal cortex

We previously reported that long-term cyclic estrogen (E) treatment reverses age-related impairment of cognitive function mediated by the dorsolateral prefrontal cortex (dlPFC) in ovariectomized (OVX) female rhesus monkeys, and that E induces a corresponding increase in spine density in layer III dl...

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Autors principals: Hao, Jiandong, Rapp, Peter R., Janssen, William G. M., Lou, Wendy, Lasley, Bill L., Hof, Patrick R., Morrison, John H.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040921/
https://ncbi.nlm.nih.gov/pubmed/17592140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704757104
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