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Genetic targeting of the kinase activity of the Met receptor in cancer cells

The development of kinase inhibitors is revolutionizing cancer treatment. Assessing the oncogenic potential of individual kinase activities and ensuring that a drug of interest acts by direct inhibition of its putative target kinase are clear priorities. We developed a genetic strategy to selectivel...

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Detalhes bibliográficos
Main Authors: Arena, Sabrina, Pisacane, Alberto, Mazzone, Massimiliano, Comoglio, Paolo Maria, Bardelli, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040912/
https://ncbi.nlm.nih.gov/pubmed/17595299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703205104
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