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Genetic targeting of the kinase activity of the Met receptor in cancer cells

The development of kinase inhibitors is revolutionizing cancer treatment. Assessing the oncogenic potential of individual kinase activities and ensuring that a drug of interest acts by direct inhibition of its putative target kinase are clear priorities. We developed a genetic strategy to selectivel...

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Autors principals: Arena, Sabrina, Pisacane, Alberto, Mazzone, Massimiliano, Comoglio, Paolo Maria, Bardelli, Alberto
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040912/
https://ncbi.nlm.nih.gov/pubmed/17595299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703205104
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