Chargement en cours...

Sphingosine 1-Phosphate pK(a) and Binding Constants: Intramolecular and Intermolecular Influences

The dissociation constant for an ionizable ligand binding to a receptor is dependent on its charge and therefore on its environmentally-influenced pK(a) value. The pK(a) values of sphingosine 1-phosphate (S1P) were studied computationally in the context of the wild type S1P(1) receptor and the follo...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Naor, Mor M., Walker, Michelle D., Van Brocklyn, James R., Tigyi, Gabor, Parrill, Abby L.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040500/
https://ncbi.nlm.nih.gov/pubmed/17467317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmgm.2007.03.004
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!