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Architecture of the yeast Rrp44–exosome complex suggests routes of RNA recruitment for 3′ end processing
The eukaryotic core exosome (CE) is a conserved nine-subunit protein complex important for 3′ end trimming and degradation of RNA. In yeast, the Rrp44 protein constitutively associates with the CE and provides the sole source of processive 3′-to-5′ exoribonuclease activity. Here we present EM recons...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2040474/ https://ncbi.nlm.nih.gov/pubmed/17942686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705526104 |
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