Modulating the RNA Processing and Decay by the Exosome: Altering Rrp44/Dis3 Activity and End-Product

In eukaryotes, the exosome plays a central role in RNA maturation, turnover, and quality control. In Saccharomyces cerevisiae, the core exosome is composed of nine catalytically inactive subunits constituting a ring structure and the active nuclease Rrp44, also known as Dis3. Rrp44 is a member of th...

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Detalhes bibliográficos
Main Authors: Reis, Filipa P., Barbas, Ana, Klauer-King, A. A., Tsanova, Borislava, Schaeffer, Daneen, López-Viñas, Eduardo, Gómez-Puertas, Paulino, van Hoof, Ambro, Arraiano, Cecília M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827031/
https://ncbi.nlm.nih.gov/pubmed/24265673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076504
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