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Modulating the RNA Processing and Decay by the Exosome: Altering Rrp44/Dis3 Activity and End-Product
In eukaryotes, the exosome plays a central role in RNA maturation, turnover, and quality control. In Saccharomyces cerevisiae, the core exosome is composed of nine catalytically inactive subunits constituting a ring structure and the active nuclease Rrp44, also known as Dis3. Rrp44 is a member of th...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3827031/ https://ncbi.nlm.nih.gov/pubmed/24265673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076504 |
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