Activation-dependent intrachromosomal interactions formed by the TNF gene promoter and two distal enhancers

Here we provide a mechanism for specific, efficient transcription of the TNF gene and, potentially, other genes residing within multigene loci. We identify and characterize highly conserved noncoding elements flanking the TNF gene, which undergo activation-dependent intrachromosomal interactions. Th...

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Bibliografske podrobnosti
Main Authors: Tsytsykova, Alla V., Rajsbaum, Ricardo, Falvo, James V., Ligeiro, Filipa, Neely, Simon R., Goldfeld, Anne E.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2007
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040403/
https://ncbi.nlm.nih.gov/pubmed/17940009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708210104
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