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Activation-dependent intrachromosomal interactions formed by the TNF gene promoter and two distal enhancers
Here we provide a mechanism for specific, efficient transcription of the TNF gene and, potentially, other genes residing within multigene loci. We identify and characterize highly conserved noncoding elements flanking the TNF gene, which undergo activation-dependent intrachromosomal interactions. Th...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2040403/ https://ncbi.nlm.nih.gov/pubmed/17940009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708210104 |
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