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The Transcription Factor NFATp Plays a Key Role in Susceptibility to TB in Mice
In T cells, the transcription factor nuclear factor of activated T cells p (NFATp) is a key regulator of the cytokine genes tumor necrosis factor (TNF) and interferon-γ (IFN-γ). Here, we show that NFATp-deficient (NFATp(−/−)) mice have a dramatic and highly significant increase in mortality after My...
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| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3402414/ https://ncbi.nlm.nih.gov/pubmed/22844476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041427 |
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