Low dose combination of morphine and Δ(9)-tetrahydrocannabinol circumvents antinociceptive tolerance and apparent desensitization of receptors

Morphine and Δ(9)-tetrahydrocannabinol (THC) produce antinociception via mu opioid and cannabinoid CB(1) receptors, respectively, located in central nervous system (CNS) regions including periaqueductal gray and spinal cord. Chronic treatment with morphine or THC produces antinociceptive tolerance a...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Smith, Paul A., Selley, Dana E., Sim-Selley, Laura J., Welch, Sandra P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040345/
https://ncbi.nlm.nih.gov/pubmed/17603035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2007.06.001
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi