Low dose combination of morphine and Δ(9)-tetrahydrocannabinol circumvents antinociceptive tolerance and apparent desensitization of receptors

Morphine and Δ(9)-tetrahydrocannabinol (THC) produce antinociception via mu opioid and cannabinoid CB(1) receptors, respectively, located in central nervous system (CNS) regions including periaqueductal gray and spinal cord. Chronic treatment with morphine or THC produces antinociceptive tolerance a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Smith, Paul A., Selley, Dana E., Sim-Selley, Laura J., Welch, Sandra P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040345/
https://ncbi.nlm.nih.gov/pubmed/17603035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2007.06.001
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