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Cannabidiol Modulation of Antinociceptive Tolerance to Δ(9)-Tetrahydrocannabinol

RATIONALE: Humans typically self-administer cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC) together repeatedly (as in cannabis, cannabis extract, or Sativex®) to relieve pain. It has been suggested that one benefit of the drug combination may be decreased tolerance development. OBJECTIVE:...

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Publicat a:Psychopharmacology (Berl)
Autors principals: Greene, Nicholas Z., Wiley, Jenny L., Yu, Zhihao, Clowers, Brian H., Craft, Rebecca M.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454895/
https://ncbi.nlm.nih.gov/pubmed/30238130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-018-5036-z
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