Squamous metaplasia amplifies pathologic epithelial-mesenchymal interactions in COPD patients

Squamous metaplasia (SM) is common in smokers and is associated with airway obstruction in chronic obstructive pulmonary disease (COPD). A major mechanism of airway obstruction in COPD is thickening of the small airway walls. We asked whether SM actively contributes to airway wall thickening through...

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Bibliographic Details
Main Authors: Araya, Jun, Cambier, Stephanie, Markovics, Jennifer A., Wolters, Paul, Jablons, David, Hill, Arthur, Finkbeiner, Walter, Jones, Kirk, Broaddus, V. Courtney, Sheppard, Dean, Barzcak, Andrea, Xiao, Yuanyuan, Erle, David J., Nishimura, Stephen L.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2007
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040320/
https://ncbi.nlm.nih.gov/pubmed/17965775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI32526
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