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Differential gene expression of p27(Kip1) and Rb knockokut pituitary tumors associated with altered growth and angiogenesis

Mice lacking the p27(Kip1) Cdk inhibitor, like mice lacking Rb, develop pituitary tumors involving pars intermedia melanotrophs, yet p27(Kip1) tumors are genetically distinct from Rb derived tumors as they exhibit haploid insufficiency. We compared tumors from mice with p27(Kip1) constitutive and ti...

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Detalhes bibliográficos
Main Authors: Chien, Wei-Ming, Garrison, Kendra, Caufield, Emily, Orthel, Jason, Fero, Matthew L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040307/
https://ncbi.nlm.nih.gov/pubmed/17361101
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