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Genetic mosaics reveal both cell-autonomous and cell-nonautonomous function of murine p27(Kip1)

Loss of the cyclin-dependent kinase inhibitor p27(Kip1) leads to an overall increase in animal growth, pituitary tumors, and hyperplasia of hematopoietic organs, yet it is unknown whether all cells function autonomously in response to p27(Kip1) activity or whether certain cells take cues from their...

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Detalhes bibliográficos
Main Authors: Chien, Wei-Ming, Rabin, Stuart, Macias, Everardo, Miliani de Marval, Paula L., Garrison, Kendra, Orthel, Jason, Rodriguez-Puebla, Marcelo, Fero, Matthew L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449657/
https://ncbi.nlm.nih.gov/pubmed/16537495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509514103
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