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T Cell-Intrinsic and Extrinsic Mechanisms of p27(Kip1) in the Regulation of CD8 T Cell Memory

CD8 T cells exhibit dynamic alterations in proliferation and apoptosis during various phases of the CD8 T cell response, but the mechanisms that regulate cellular proliferation from the standpoint of CD8 T cell memory are not well defined. The cyclin-dependent kinase inhibitor p27(Kip1) functions as...

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Detalhes bibliográficos
Main Authors: Jatzek, Anna, Tejera, Melba Marie, Plisch, Erin H., Fero, Matthew L., Suresh, M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570738/
https://ncbi.nlm.nih.gov/pubmed/23207280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2012.71
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