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Signal Integration by Akt Regulates CD8 TCell Effector and Memory Differentiation

During a T cell response, the effector CTL pool contains two cellular subsets: short-lived effector cells (SLECs), a majority of which are destined for apoptosis, and the memory precursor effector cells (MPECs) that differentiate into memory cells. Understanding the mechanisms that govern the differ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kim, Eui Ho, Sullivan, Jeremy A., Plisch, Erin H., Tejera, Melba Marie, Jatzek, Anna, Choi, Kwan Yong, Suresh, M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331885/
https://ncbi.nlm.nih.gov/pubmed/22467649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103568
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