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p27(Kip1) Negatively Regulates the Magnitude and Persistence of CD4 T Cell Memory

Much is known about the differentiation of naïve T cells into distinct lineages of effector cells, but the molecular mechanisms underlying the generation and maintenance of CD4 T cell memory are poorly characterized. Our studies ascribe a novel role for the cell cycle regulator p27(Kip1), as a promi...

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Detalhes bibliográficos
Main Authors: Jatzek, Anna, Tejera, Melba Marie, Singh, Anju, Sullivan, Jeremy A., Plisch, Erin H., Suresh, M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504176/
https://ncbi.nlm.nih.gov/pubmed/23071285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201482
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