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p27(Kip1) Negatively Regulates the Magnitude and Persistence of CD4 T Cell Memory
Much is known about the differentiation of naïve T cells into distinct lineages of effector cells, but the molecular mechanisms underlying the generation and maintenance of CD4 T cell memory are poorly characterized. Our studies ascribe a novel role for the cell cycle regulator p27(Kip1), as a promi...
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Autori principali: | , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2012
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3504176/ https://ncbi.nlm.nih.gov/pubmed/23071285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201482 |
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