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Genetic mosaics reveal both cell-autonomous and cell-nonautonomous function of murine p27(Kip1)

Loss of the cyclin-dependent kinase inhibitor p27(Kip1) leads to an overall increase in animal growth, pituitary tumors, and hyperplasia of hematopoietic organs, yet it is unknown whether all cells function autonomously in response to p27(Kip1) activity or whether certain cells take cues from their...

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Autors principals: Chien, Wei-Ming, Rabin, Stuart, Macias, Everardo, Miliani de Marval, Paula L., Garrison, Kendra, Orthel, Jason, Rodriguez-Puebla, Marcelo, Fero, Matthew L.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449657/
https://ncbi.nlm.nih.gov/pubmed/16537495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509514103
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