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Genetic mosaics reveal both cell-autonomous and cell-nonautonomous function of murine p27(Kip1)

Loss of the cyclin-dependent kinase inhibitor p27(Kip1) leads to an overall increase in animal growth, pituitary tumors, and hyperplasia of hematopoietic organs, yet it is unknown whether all cells function autonomously in response to p27(Kip1) activity or whether certain cells take cues from their...

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Autori principali: Chien, Wei-Ming, Rabin, Stuart, Macias, Everardo, Miliani de Marval, Paula L., Garrison, Kendra, Orthel, Jason, Rodriguez-Puebla, Marcelo, Fero, Matthew L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449657/
https://ncbi.nlm.nih.gov/pubmed/16537495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509514103
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