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Crystal structure of Dcp1p and its functional implications in mRNA decapping
A major pathway of eukaryotic mRNA turnover begins with deadenylation, followed by decapping and 5′→3′ exonucleolytic degradation. A critical step in this pathway is decapping, which is carried out by an enzyme composed of Dcp1p and Dcp2p. The crystal structure of Dcp1p shows that it markedly resemb...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2040073/ https://ncbi.nlm.nih.gov/pubmed/14758354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb730 |
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