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Structural basis of Dcp2 recognition and activation by Dcp1
A critical step in mRNA degradation is the removal of the 5' cap structure, which is catalyzed by the Dcp1-Dcp2 complex. The crystal structure of a S. pombe Dcp1p-Dcp2n complex combined with small-angle X-ray scattering analysis (SAXS) reveals that Dcp2p exists in open and closed conformations,...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2323275/ https://ncbi.nlm.nih.gov/pubmed/18280239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.01.002 |
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