Structural basis of Dcp2 recognition and activation by Dcp1

A critical step in mRNA degradation is the removal of the 5' cap structure, which is catalyzed by the Dcp1-Dcp2 complex. The crystal structure of a S. pombe Dcp1p-Dcp2n complex combined with small-angle X-ray scattering analysis (SAXS) reveals that Dcp2p exists in open and closed conformations,...

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Detaylı Bibliyografya
Asıl Yazarlar: She, Meipei, Decker, Carolyn J., Svergun, Dmitri I., Round, Adam, Chen, Nan, Muhlrad, Denise, Parker, Roy, Song, Haiwei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323275/
https://ncbi.nlm.nih.gov/pubmed/18280239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.01.002
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