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Decapping activators in Saccharomyces cerevisiae act by multiple mechanisms

Eukaryotic mRNA degradation often occurs in a process whereby translation initiation is inhibited and the mRNA is targeted for decapping. In yeast cells, Pat1, Scd6, Edc3, and Dhh1 all function to promote decapping by unknown mechanism(s). We demonstrate that purified Scd6 and a region of Pat1 direc...

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Main Authors: Nissan, Tracy, Rajyaguru, Purusharth, She, Meipei, Song, Haiwei, Parker, Roy
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946179/
https://ncbi.nlm.nih.gov/pubmed/20832728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.08.025
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