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Decapping activators in Saccharomyces cerevisiae act by multiple mechanisms

Eukaryotic mRNA degradation often occurs in a process whereby translation initiation is inhibited and the mRNA is targeted for decapping. In yeast cells, Pat1, Scd6, Edc3, and Dhh1 all function to promote decapping by unknown mechanism(s). We demonstrate that purified Scd6 and a region of Pat1 direc...

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Detalhes bibliográficos
Main Authors: Nissan, Tracy, Rajyaguru, Purusharth, She, Meipei, Song, Haiwei, Parker, Roy
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946179/
https://ncbi.nlm.nih.gov/pubmed/20832728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.08.025
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