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Decapping activators in Saccharomyces cerevisiae act by multiple mechanisms
Eukaryotic mRNA degradation often occurs in a process whereby translation initiation is inhibited and the mRNA is targeted for decapping. In yeast cells, Pat1, Scd6, Edc3, and Dhh1 all function to promote decapping by unknown mechanism(s). We demonstrate that purified Scd6 and a region of Pat1 direc...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2946179/ https://ncbi.nlm.nih.gov/pubmed/20832728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.08.025 |
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