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Decapping activators in Saccharomyces cerevisiae act by multiple mechanisms

Eukaryotic mRNA degradation often occurs in a process whereby translation initiation is inhibited and the mRNA is targeted for decapping. In yeast cells, Pat1, Scd6, Edc3, and Dhh1 all function to promote decapping by unknown mechanism(s). We demonstrate that purified Scd6 and a region of Pat1 direc...

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Hlavní autoři: Nissan, Tracy, Rajyaguru, Purusharth, She, Meipei, Song, Haiwei, Parker, Roy
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946179/
https://ncbi.nlm.nih.gov/pubmed/20832728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.08.025
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