טוען...
Recombinant human parainfluenza virus type 2 vaccine candidates containing a 3′ genomic promoter mutation and L polymerase mutations are attenuated and protective in non-human primates
Previously, we identified several attenuating mutations in the L polymerase protein of human parainfluenza virus type 2 (HPIV2) and genetically stabilized those mutations using reverse genetics (Nolan et al., 2005). Here we describe the discovery of an attenuating mutation at nucleotide 15 (15(T→C))...
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| Main Authors: | , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2007
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2040028/ https://ncbi.nlm.nih.gov/pubmed/17658669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.06.028 |
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