Anx7 is required for nutritional control of gene expression in mouse pancreatic islets of Langerhans.

BACKGROUND: Gene expression in islets of Langerhans is profoundly sensitive to glucose and other nutrients. Islets of Langerhans in the Anx7(+/-) knockout mouse exhibit a profound reduction in ITPR3 protein expression, defective intracellular calcium signaling, and defective insulin secretion. Addit...

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Main Authors: Srivastava, Meera, Eidelman, Ofer, Leighton, Ximena, Glasman, Mirta, Goping, Gertrude, Pollard, Harvey B.
格式: Artigo
語言:Inglês
出版: 2002
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2039971/
https://ncbi.nlm.nih.gov/pubmed/12606813
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