Diverse Effects of ANXA7 and p53 on LNCaP Prostate Cancer Cells Are Associated with Regulation of SGK1 Transcription and Phosphorylation of the SGK1 Target FOXO3A

Tumor suppressor function of the calcium/phospholipid-binding Annexin-A7 (ANXA7) has been shown in Anxa7-deficient mice and validated in human cancers. In the androgen-resistant prostate cancer cells, ANXA7 and p53 showed similar cytotoxicity levels. However, in the androgen-sensitive LNCaP, ANXA7 g...

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Detalhes bibliográficos
Main Authors: Srivastava, Meera, Leighton, Ximena, Starr, Joshua, Eidelman, Ofer, Pollard, Harvey B.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016907/
https://ncbi.nlm.nih.gov/pubmed/24864229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/193635
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