Melatonin Induces Apoptotic Cell Death via p53 in LNCaP Cells

In this study, we examined whether melatonin promotes apoptotic cell death via p53 in prostate LNCaP cells. Melatonin treatment significantly curtailed the growth of LNCaP cells in a dose- and time-dependent manner. Melatonin treatment (0 to 3 mM) induced the fragmentation of poly(ADP-ribose) polyme...

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Bibliographic Details
Main Authors: Kim, Chi Hyun, Yoo, Yeong-Min
Format: Artigo
Language:Inglês
Published: The Korean Physiological Society and The Korean Society of Pharmacology 2010
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034115/
https://ncbi.nlm.nih.gov/pubmed/21311676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2010.14.6.365
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