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Melatonin Induces Apoptotic Cell Death via p53 in LNCaP Cells
In this study, we examined whether melatonin promotes apoptotic cell death via p53 in prostate LNCaP cells. Melatonin treatment significantly curtailed the growth of LNCaP cells in a dose- and time-dependent manner. Melatonin treatment (0 to 3 mM) induced the fragmentation of poly(ADP-ribose) polyme...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Korean Physiological Society and The Korean Society of Pharmacology
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3034115/ https://ncbi.nlm.nih.gov/pubmed/21311676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2010.14.6.365 |
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