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Melatonin Induces Apoptotic Cell Death via p53 in LNCaP Cells

In this study, we examined whether melatonin promotes apoptotic cell death via p53 in prostate LNCaP cells. Melatonin treatment significantly curtailed the growth of LNCaP cells in a dose- and time-dependent manner. Melatonin treatment (0 to 3 mM) induced the fragmentation of poly(ADP-ribose) polyme...

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書目詳細資料
Main Authors: Kim, Chi Hyun, Yoo, Yeong-Min
格式: Artigo
語言:Inglês
出版: The Korean Physiological Society and The Korean Society of Pharmacology 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034115/
https://ncbi.nlm.nih.gov/pubmed/21311676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2010.14.6.365
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