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Crystal structure of the BIR1 domain of XIAP In two crystal forms
X-linked inhibitor of apoptosis (XIAP) is a potent negative regulator of apoptosis. It also plays a role in BMP signaling, TGF-β signaling, and copper homeostasis. Previous structural studies have shown that the BIR2 and BIR3 domains of XIAP interact with the IAP-binding-motifs (IBM) in several apop...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2039701/ https://ncbi.nlm.nih.gov/pubmed/17698078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.07.019 |
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