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Human cytomegalovirus IE1 and IE2 proteins are mutagenic and mediate “hit-and-run” oncogenic transformation in cooperation with the adenovirus E1A proteins

Some epidemiological studies have suggested a possible link between human cytomegalovirus (HCMV) infection and various malignancies, and HCMV has been shown to transform cultured cells. However, viral DNA is not detected in most transformants, and the mechanism by which HCMV might contribute to onco...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Shen, Yuqiao, Zhu, Hua, Shenk, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20371/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9096395/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.7.3341
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