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Human cytomegalovirus IE1 and IE2 proteins are mutagenic and mediate “hit-and-run” oncogenic transformation in cooperation with the adenovirus E1A proteins

Some epidemiological studies have suggested a possible link between human cytomegalovirus (HCMV) infection and various malignancies, and HCMV has been shown to transform cultured cells. However, viral DNA is not detected in most transformants, and the mechanism by which HCMV might contribute to onco...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Shen, Yuqiao, Zhu, Hua, Shenk, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20371/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9096395/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.7.3341
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