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PEG-b-PPA/DNA micelles improve transgene expression in rat liver through intrabiliary infusion
We have developed a new block copolymer gene carrier that comprises of a polyethylene glycol segment and a degradable cationic polyphosphoramidate (PPA) segment. This PEG-b-PPA copolymer carrier formed micelles upon condensation with plasmid DNA in aqueous solution. PEG-b-PPA/DNA micelles exhibited...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2035949/ https://ncbi.nlm.nih.gov/pubmed/17640758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2007.06.014 |
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