Chitosan-DNA nanoparticles delivered by intrabiliary infusion enhance liver-targeted gene delivery

The goal of this study was to examine the efficacy of liver-targeted gene delivery by chitosan-DNA nanoparticles through retrograde intrabiliary infusion (RII). The transfection efficiency of chitosan-DNA nanoparticles, as compared with PEI-DNA nanoparticles or naked DNA, was evaluated in Wistar rat...

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Autors principals: Dai, Hui, Jiang, Xuan, Tan, Geoffrey CY, Chen, Yong, Torbenson, Michael, Leong, Kam W, Mao, Hai-Quan
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2006
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Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828073/
https://ncbi.nlm.nih.gov/pubmed/17369870
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