Chitosan-DNA nanoparticles delivered by intrabiliary infusion enhance liver-targeted gene delivery

The goal of this study was to examine the efficacy of liver-targeted gene delivery by chitosan-DNA nanoparticles through retrograde intrabiliary infusion (RII). The transfection efficiency of chitosan-DNA nanoparticles, as compared with PEI-DNA nanoparticles or naked DNA, was evaluated in Wistar rat...

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Hlavní autoři: Dai, Hui, Jiang, Xuan, Tan, Geoffrey CY, Chen, Yong, Torbenson, Michael, Leong, Kam W, Mao, Hai-Quan
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2006
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828073/
https://ncbi.nlm.nih.gov/pubmed/17369870
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