Antigen expression by dendritic cells correlates with the therapeutic effectiveness of a model recombinant poxvirus tumor vaccine

Recombinant poxviruses encoding tumor-associated antigens (TAA) are attractive as candidate cancer vaccines. Their effectiveness, however, will depend upon expression of the TAA in appropriate antigen-presenting cells. We have used a murine model in which the TAA is β-galactosidase (β-gal) and a pan...

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Bibliographic Details
Main Authors: Bronte, Vincenzo, Carroll, Miles W., Goletz, Theresa J., Wang, Michael, Overwijk, Willem W., Marincola, Francesco, Rosenberg, Steven A., Moss, Bernard, Restifo, Nicholas P.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1997
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC20343/
https://ncbi.nlm.nih.gov/pubmed/9096367
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