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IL-2 Enhances the Function of Recombinant Poxvirus-Based Vaccines in the Treatment of Established Pulmonary Metastases

Neoplastic cells are generally poor immunogens. Transfection of the murine tumor CT-26 with β-galactosidase (β-gal), a proteinfrom Escherichia coli, did not alter its growth rate in vivo, or its lethality, and did not elicit a measurable anti-β-gal immune response. Immunization with β-gal-expressing...

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Detalhes bibliográficos
Main Authors: Bronte, Vincenzo, Tsung, Kangla, Rao, Jay B., Chen, Pauline W., Wang, Michael, Rosenberg, Steven A., Restifo, Nicholas P.
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2041892/
https://ncbi.nlm.nih.gov/pubmed/7730632
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