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IL-12 Is an Effective Adjuvant to Recombinant Vaccinia Virus-Based Tumor Vaccines: Enhancement by Simultaneous B7-1 Expression

A number of cytokines and costimulatory molecules involved in immune activation have recently been identified including IL-12, a heterodimeric cytokine that supports the development of cell-mediated immunity, and B7-1, a costimulatory molecule involved in the activation of T lymphocytes. We explored...

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Autors principals: Rao, Jay B., Chamberlain, Ronald S., Bronte, Vincenzo, Carroll, Miles W., Irvine, Kari R., Moss, Bernard, Rosenberg, Steven A., Restifo, Nicholas P.
Format: Artigo
Idioma:Inglês
Publicat: 1996
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952187/
https://ncbi.nlm.nih.gov/pubmed/8617961
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