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Construction and Characterization of a Triple-Recombinant Vaccinia Virus Encoding B7-1, Interleukin 12, and a Model Tumor Antigen

BACKGROUND: Construction of recombinant viruses that can serve as vaccines for the treatment of experimental murine tumors has recently been achieved. The cooperative effects of immune system modulators, including cytokines such as interleukin 12 (IL-12) and costimulatory molecules such as B7-1, may...

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Hlavní autoři: Carroll, Miles W., Overwijk, Willem W., Surman, Deborah R., Tsung, Kangla, Moss, Bernard, Restifo, Nicholas P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 1998
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2249692/
https://ncbi.nlm.nih.gov/pubmed/9862625
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