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Anti-Tumor Activity of Cytotoxic T Lymphocytes Elicited with Recombinant and Synthetic Forms of a Model Tumor-Associated Antigen

The recent cloning of tumor-associated antigens (TAAs) recognized by CD8 (+) T lymphocytes (T(CD8(−))) has made it possible to use recombinant and synthetic forms of TAAs to generate T(CD8(−)) with anti-tumor activity. To explore new therapeutic strategies in a mouse model, we retrovirally transduce...

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Autors principals: Wang, Michael, Chen, Pauline W., Bronte, Vincenzo, Rosenberg, Steven A., Restifo, Nicholas P.
Format: Artigo
Idioma:Inglês
Publicat: 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2555984/
https://ncbi.nlm.nih.gov/pubmed/8770769
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