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A unique mechanism of β-blocker action: Carvedilol stimulates β-arrestin signaling

For many years, β-adrenergic receptor antagonists (β-blockers or βAR antagonists) have provided significant morbidity and mortality benefits in patients who have sustained acute myocardial infarction. More recently, β-adrenergic receptor antagonists have been found to provide survival benefits in pa...

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Autores principales: Wisler, James W., DeWire, Scott M., Whalen, Erin J., Violin, Jonathan D., Drake, Matthew T., Ahn, Seungkirl, Shenoy, Sudha K., Lefkowitz, Robert J.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034221/
https://ncbi.nlm.nih.gov/pubmed/17925438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707936104
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