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Expression of tumour-suppressor gene Rb, apoptosis-suppressing protein Bcl-2 and c-Myc have no independent prognostic value in renal adenocarcinoma.

The expression of retinoblastoma (Rb), c-Myc and Bcl-2 proteins was studied by immunohistochemical methods in 104 cases of renal adenocarcinoma. One tumour was completely negative for Rb protein and altered expression pattern was detected in 36% of cases. A low fraction of Rb-positive nuclei was rel...

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Autori principali: Lipponen, P., Eskelinen, M., Syrjänen, K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1995
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033746/
https://ncbi.nlm.nih.gov/pubmed/7710955
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