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C-MYC–induced Apoptosis in Polycystic Kidney Disease Is Bcl-2 and p53 Independent

The SBM mouse is a unique transgenic model of polycystic kidney disease (PKD) induced by the dysregulated expression of c-myc in renal tissue. In situ hybridization analysis demonstrated intense signal for the c-myc transgene overlying tubular cystic epithelium in SBM mice. Renal proliferation index...

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Bibliografiske detaljer
Main Authors: Trudel, Marie, Lanoix, Jacqueline, Barisoni, Laura, Blouin, Marie-José, Desforges, Marc, L'Italien, Catherine, D'Agati, Vivette
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199149/
https://ncbi.nlm.nih.gov/pubmed/9382886
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