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Studies of the regulation and function of the G(s)α gene Gnas using gene targeting technology

The heterotrimeric G protein α-subunit G(s)α is ubiquitously expressed and mediates receptor-stimulated intracellular cAMP generation. Its gene Gnas is a complex imprinted gene which uses alternative promoters and first exons to generate other gene products, including the G(s)α isoform XLαs and the...

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Detalhes bibliográficos
Main Authors: Weinstein, Lee S., Xie, Tao, Zhang, Qing-Hong, Chen, Min
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2031856/
https://ncbi.nlm.nih.gov/pubmed/17588669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2007.03.013
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