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New Insights into the Mechanism of Alzheimer Amyloid-β Fibrillogenesis Inhibition by N-Methylated Peptides
Alzheimer's disease is a debilitating neurodegenerative disorder associated with the abnormal self-assembly of amyloid-β (Aβ) peptides into fibrillar species. N-methylated peptides homologous to the central hydrophobic core of the Aβ peptide are potent inhibitors of this aggregation process. In...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2025672/ https://ncbi.nlm.nih.gov/pubmed/17631541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.112086 |
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