Clinical testing of the radiosensitizer Ro 07-0582: experience with multiple doses.

The hypoxic cell radiosensitizer, Ro 07-0582, has now been given in multiple doses to 16 patients. They have received a total of 15-51 g in 3-20 doses. Immediate tolerance was good, and satisfactory plasma levels of the drug were consistently obtained. Neurotoxicity was, however, troublesome: convul...

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Bibliografiska uppgifter
Huvudupphovsmän: Dische, S., Saunders, M. I., Lee, M. E., Adams, G. E., Flockhart, I. R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 1977
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2025511/
https://ncbi.nlm.nih.gov/pubmed/861146
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