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Effect of hyperthermia on differential cytotoxicity of a hypoxic cell radiosensitizer, Ro-07-0582, on mammalian cells in vitro.

There is now evidence that several classes of nitro compounds which have been used as radiosensitizers also function as cytotoxic agents specific for hypoxic cells. The 2-nitroimidazole, Ro-07-0582, (1-(2-nitroimidazol-1-yl)-3-methoxy-2-propanol) is a compound of this type, and its effectiveness as...

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Hlavní autoři: Stratford, I. J., Adams, G. E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1977
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2025287/
https://ncbi.nlm.nih.gov/pubmed/856238
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