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Targeted expression of a multifunctional chimeric neurotrophin in the lesioned sciatic nerve accelerates regeneration of sensory and motor axons

Peripheral nerve injury markedly regulates expression of neurotrophins and their receptors in the lesioned nerve. However, the role of endogenously produced neurotrophins in the process of nerve regeneration is unclear. Expression of a multifunctional neurotrophin, pan-neurotrophin-1 (PNT-1), was ta...

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Библиографические подробности
Главные авторы: Funakoshi, Hiroshi, Risling, Mårten, Carlstedt, Thomas, Lendahl, Urban, Timmusk, Tõnis, Metsis, Madis, Yamamoto, Yuji, Ibáñez, Carlos F.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 1998
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC20250/
https://ncbi.nlm.nih.gov/pubmed/9560265
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