Targeted expression of a multifunctional chimeric neurotrophin in the lesioned sciatic nerve accelerates regeneration of sensory and motor axons

Peripheral nerve injury markedly regulates expression of neurotrophins and their receptors in the lesioned nerve. However, the role of endogenously produced neurotrophins in the process of nerve regeneration is unclear. Expression of a multifunctional neurotrophin, pan-neurotrophin-1 (PNT-1), was ta...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Funakoshi, Hiroshi, Risling, Mårten, Carlstedt, Thomas, Lendahl, Urban, Timmusk, Tõnis, Metsis, Madis, Yamamoto, Yuji, Ibáñez, Carlos F.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20250/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9560265/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.9.5269
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