Targeted expression of a multifunctional chimeric neurotrophin in the lesioned sciatic nerve accelerates regeneration of sensory and motor axons

Peripheral nerve injury markedly regulates expression of neurotrophins and their receptors in the lesioned nerve. However, the role of endogenously produced neurotrophins in the process of nerve regeneration is unclear. Expression of a multifunctional neurotrophin, pan-neurotrophin-1 (PNT-1), was ta...

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Εκδόθηκε σε:	Proc Natl Acad Sci U S A
Κύριοι συγγραφείς:	Funakoshi, Hiroshi, Risling, Mårten, Carlstedt, Thomas, Lendahl, Urban, Timmusk, Tõnis, Metsis, Madis, Yamamoto, Yuji, Ibáñez, Carlos F.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	National Academy of Sciences 1998
Θέματα:	Biological Sciences
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20250/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9560265/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.9.5269
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