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Neurotrophins induce fission of mitochondria along embryonic sensory axons

Neurotrophins are growth factors that have a multitude of roles in the nervous system. We report that neurotrophins induce the fission of mitochondria along embryonic chick sensory axons driven by combined PI3K and Mek-Erk signaling. Following an initial burst of fission, a new steady state of neuro...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Armijo-Weingart, Lorena, Ketschek, Andrea, Sainath, Rajiv, Pacheco, Almudena, Smith, George M, Gallo, Gianluca
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887118/
https://ncbi.nlm.nih.gov/pubmed/31789589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49494
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